MICROBIO 160 Lecture Notes - Lecture 19: Squamous Cell Skin Cancer, Basal-Cell Carcinoma, Squamous Cell Carcinoma

• School: UMASS-Amherst
• Department: Microbiology
• Course: MICROBIO 160
• Professor: Wilmore Welby

Document Summary

Uvb is the main cause of skin cancer (also 1,000 times more effective in causing sunburn). Oxidize lipids and produces harmful free radicals. Causes inflammation, which also produces free radicals, particularly nitrogen radicals. Disrupts cell communication and causes expression of stress response genes. Weakens the immune responses of the skin. Skin cancer is a type of cancer that develops in the layers of the skin. There are two main types of skin cancer: Caucasians are at highest risk of developing skin cancer, especially men over 50. 60-75% of skin cancer tumors in asians, african-americans, indonesians, filipinos, and. 5-year survival rate for all skin cancers: Proportion of incidence and mortality for different types of skin cancer. Highest cause of cases = basal cell carcinoma. Origin of the three types of skin cancer. Melanoma starts in the basal layers of the skin and instead of going up to the surface, it does down deeper into the skin.