PSYCH 330 Lecture Notes - Lecture 10: Pinocytosis, Ligand-Gated Ion Channel, Reuptake

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Pinocytosis: removal of fusion pores from the presynaptic membrane. Each type of receptor can bind only 1 type of nt, or ligand. Like a lock will only fit one key. Each neurotransmitter can bind to a few different types of receptors. Like a key will fit your front door, back door, garage door, etc. G proteins open other ion channels or activate second messenger pathways. Autoreceptors: nt receptors on presynaptic neurons inhibit further nt production or release. Presynaptic neuron releases neurotransmitter directly onto a specific location on postsynaptic neuron. Neuron contains terminal varicosities neurotransmitters to affect multiple neurons area. A synapse that does not use nts; neurons make direct contact through large channels (connexons) More action potentials in the presynaptic neuron, more ca++ entering the presynaptic neuron, fusion of more synaptic vesicles w/ the presynaptic membrane. If terminal a causes esps in terminal b and terminal b causes ipsps in neuron.

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