PSYCH 330 Lecture Notes - Lecture 13: Neuroendocrinology, Steroid Hormone Receptor, Adrenal Gland

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Interaction between the nervous system and the endocrine system. Endocrine system secretes hormones: chemical secreted by a gland that travels through the bloodstream and regulates target organs and tissues. Neuroendocrine cells receive nt signals, integrate psps, fire aps. Cortisol is released from adrenal glands into bloodstream during fight/flight response. Two mechanisms of hormone action: peptides and amines bind to receptors on cell membrane, activates second messengers i. Multiplicity of hormone action: can respond to more than one hormone. Some hormones affect more than one target; some targets. Organizational effects: relatively permanent effects on body structure/function,critical periods. Activational effects: immediate, reversible effects of hormones, behavioral effects. Negative feedback control: output of the hormone feeds back and inhibits further release, set point can be change for various circumstances or by experiences, regulated by hypothalamus, like a thermostat. Pituitary gland: secretion of hormones is controlled by hypothalamus. Neuroendocrine cells in hypothalamus project axons into posterior pituitary and synapse onto capillaries.

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