EHS 260 Lecture Notes - Lecture 20: Combined Oral Contraceptive Pill, Random Assignment
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Participants are selected based on the presence (a case) or a absence (a control) of a disease. Cases and controls are matched on several possible causes of disease. Comparisons of frequency of past exposure to other potential risk factors are made between the two groups. Difficult to obtain a good control group. If you have experienced an event, such as cancer diagnosis, you may think more about why this occurred compared to a control person. Retrospective cohort study: outcome and exposure occurred in the past. From medical records, identify a group of women who were using oral contraceptive pills (ocps)10 years ago and a group of women who were not using ocps. Interview the women or use medical records to determine their history of heart disease from the point of ocp use to the present. A group of individuals is selected at random from a defined population.