EHS 260 Lecture Notes - Lecture 19: Pneumocystis Pneumonia, Case Series, Sarcoma

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Describe the experience of a single patient or a group of patients with similar diagnosis. Typically, an observant clinician reports an unusual feature of a disease, a patient"s exposure history, or unusual medical event. May lead to formulation of new hypotheses. A series of unusual cases may prompt further investigations with more rigorous study designs. One of the most common types of studies published in medical journals. May occur in a relatively short time period: can indicate the beginning or presence of an epidemic, hypothesis through investigation of experiences of affected people. Identification of possible causal factors - analytic study to compare experiences of the case series with a group of individuals who did not develop the disease. Between oct 1980 and may 1981, 5 cases of pneumocystis carinii pneumonia were reported among young, previously healthy, homosexual men in l. a. Previously occurred only in older, immunosuppressed cancer patients.

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