EHS 260 Lecture Notes - Lecture 28: Relative Risk, Cardiovascular Disease, Physical Activity Level
13 May 2016
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Document Summary
Aerobics center longitudinal study (acls: n=>25,000 men. Compared to men who were fit (quintile 2-5) those who were unfit (quintile 1) had 1. 7 times the relative risk of cvd. Compared to men who did not smoke, smokers had 1. 57 times the risk of cvd. Compared to those with normal chol, those with high chol had 1. 65 times the risk of. Men who were unfit on first assessment (quintile 1) but had improved their fitness five years later experienced a 52% lower age-adjusted risk of cvd mortality than men who remained unfit. Rrelationship between physical activity/fitness and risk for chd: Strong (relative risk similar to that associated with smoking, high cholesterol and hypertension); Graded, i. e. a dose response has been demonstrated; Stroke and chd share similar pathophysiology and risk factors. There are fewer studies, and effect is less convincing. The nurses" health study is among the largest and longest running investigations of factors that influence women"s health.
