EHS 350 Lecture Notes - Lecture 15: Intrapleural Pressure, Transpulmonary Pressure, Extracellular Fluid

• School: UMass Boston
• Department: Exercise and Health Science
• Course: EHS 350
• Professor: Kai Zou

Document Summary

Makes up to keep alveoli open. Free alveolar macrophages - aka dust cells p. 821 roam surface of alveolus to pick up bacteria, viruses travel out of alveolus. 2 million of these cells are removed in an hour: capillary part that rests on alveolus is simple squamous cell and its basement membrane interstitial fluid - To get from lumen of alveolus to lumen of capillaries : Capillary surfactant layer thin fluid layer than lines alveolus alveoli epithelium - type 1 and type 2 alveolar basement membrane interstitial space capillary basement membrane capillary endothelium partial pressure of o2 is160. Mechanics of breathing - 823 to 827: atmospheric pressure (760 mmhg) b) intrapulmonary/ intra alveolar/ intrapulmonic (760 +/-3 mmhg) i) Describe pressures b/w lungs c) intrathoracic/intrapleural (ipp) (756 mmhg) +/- 3: transpulmonary pressure. ** diff b/w intrapulmonary and intrapleural/ intrathoracic pressure pressure b/w both will always be -4mmhg changes in pressure affects how alveoli expands: inspiration, boyle"s law.