BIOL 1010 Lecture Notes - Sickle-Cell Disease, Chromosome, Alap
Document Summary
See it usually in women (if in malesomething wrong) Need both x chromosomes in beginning, but later, it becomes inactivated --> bar body. If it"s in a male, might be xxy, kleinfelter syndromein this case, one of the x"s becomes a bar body. Correlation/causationhave set of data very similar to another set of data. -ex: distribution of malaria and sickle cell anemia in africathere"s a connection, but not sure that sickle cell causes maleria or vice versa -->correlated, but not necessarily 1 causing the other. When have sickle cell trait but not full gene, have codominancedon"t have full disastrous effects, but have some of those cells, so can resist anemia. Cystic fibrosis has same situation as sickle cell. Heterozygous traits helped european population w/ cholera and losing digestive fluids b/c of diarrhea. Because of that correlation, we looked for the reason lysosomes and peroxisomes. Extension of golgi aparatus (one of the things golgi aparatus sends in vessicles)
