PERI 8120 Lecture 50: perio final exam review session 3

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Know what mechanical and chemical duisruption are. And know low-dose docycycline periostat is the other name. (page 74?) And know the doses (the red on page 75: mech: srp, chem. Antimicrobials systemic antibiotics, local delivery antibiotics (directly to the sulcus), topical antimicrobials. Low-dose doxycycline changes host response to bacteria. 20mg bid (twice a day) for 3-9 months. Therapeutic effect via enzyme, cytokine, and osteoclast inhibition. Know what an sdd is, what the combination is/characteristic is, that should be sufficient: sdd = sub-antimicrobial dose doxycycline. Clinical benefit for sdd compared w/ srp alone. Page 77; very important slide: when used w/ srp, systemic antibiotics used as adjuncts proved to create improvements, must disrupt biofilm before administering the systemic ab. Know when you need to do microbial testing (page. 84?: aggressive periodontitis (localized or generalized, refractory periodontitis, medical conditions predisposing you to pd (diabetes, peri-implantitis, when not to do microbial testing. Healthy patients (except family members of those w/ agg periodontitis)

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