BIOL 540 Lecture Notes - Lecture 26: Glucose-6-Phosphate Isomerase, Endoplasmic Reticulum, Glut4
Document Summary
Glycolytic pathway can be broken down into parts c part"t priming. 6 phosphate phosphoglucose isomerase converts glucose 6 phosphate to fructose 6 phosphate. 6 phosphofructose l kinase catalyzes the addition of another phosphate l from atp to the 1 position of fructose 6 phosphate to yieldfructose 1,6 biphosphate. 2 stage 2 splitting fructose 1 6 biphosphate aldolaseacleaves the molecule. 2 three carbonmolecules into dihydroxyacetone phosphatedhap and glyceraldehyde 3 phosphate. Gap next stage will only include but remember 2. Gap will move on from this it has to be doubled stage so in stage 3. Glyceraldehyde 3 phosphate gap dehydrogenase oxidizes the aldehyde to a carboxylicacid and reduces. Nadt to nadh producing 1,3 biphosphoglycerate this atp is the freeone from the investment phosphoglycerate kinase adds a phosphate to adp to make atp and yields a 3 phosphoglycerate this step is reversible. 3 phosphoglycerate is phosphorylated carbon intermediate 2,3 by a biphosphoglycerate needed in catalyticamounts very small amounts.
