BIOL 540 Lecture Notes - Lecture 41: Farnesyl-Diphosphate Farnesyltransferase, Acetoacetyl-Coa, Acetyl-Coa
Document Summary
1 acetoacetylcoa thiolase catalyzes the condensation of form acetoacetyl coa two acetyl coa molecules to. 2 hmg ga synthase catalyzes the reaction by which an. Coa molecule additional acetyl coa is added to the acetoacetyl two forms of hmg coa synthase cytosolic er and mitochondrial isoforms. Hmg coa synthase is most active in the found in all cells but are liver is a. 3 hmg reductase uses 2 molecule of nadph to hydrolyze the reduce hmg to mevalonate thioester linkage of hmg 60a and first committed step of cholesterol biosynthesis. Vinny will be lowered makes it a better substrate for protein degradation is converted to. 3 isopentyl pyrophosphate combined sequentially by a geranyltransferase. 5 carbons each are cytosolic enzyme to yield 15 carbon framesyl pyrophosphate diphosphate pyrophosphate kinase kinase decarboxylate uses atp one of the three isopentyl pyrophosphate must be converted to a dimethylallyl pyrophosphate first costs 3 atp.