BIBB 150 Lecture Notes - Lecture 7: Congenital Adrenal Hyperplasia, Paramesonephric Duct, Mesonephric Duct

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Sex determination: sex chromosomes determine the general course of sexual development. Sry gene: only on the y chromosome. Ovaries develop in the absence of this gene/chromosome. (epigenetics and sex determination): moderations in gene expression. Sex chromosome mosaicism - a person has more than one component of sex chromosomes (just a strange variation of different chromosomes in different places). Hypothalamus: female brains are more sensitive to estrogen, male brains are more sensitive to androgen. Mullerian duct - ducts found in both male and female fetuses; in females the wolffian ducts degenerate, and turn into the fallopian tubes, uterus, and upper vagina. Wolffian duct - mullerian ducts degenerate. turn into the epididymis, vas deferens, and ejactulatory duct when the mullerian-inhibiting substance is emitted in the womb. Intersexuality - a condition in which the individual has a mixture of male and female reproductive structures, so it"s not clear at birth which sex they are.

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