BPS 432 Lecture Notes - Lecture 12: Postherpetic Neuralgia, Trigeminal Neuralgia, Tramadol

• School: URI
• Department: Biomedical and Pharmaceutical Sciences
• Course: BPS 432
• Professor: Kovoor Abraham

Document Summary

Pai(cid:374) is des(cid:272)(cid:396)i(cid:271)ed as (cid:862)a(cid:374) u(cid:374)pleasa(cid:374)t se(cid:374)so(cid:396)(cid:455) a(cid:374)d e(cid:373)otio(cid:374)al e(cid:454)pe(cid:396)ie(cid:374)(cid:272)e (cid:449)ith a(cid:272)tual o(cid:396) pote(cid:374)tial tissue da(cid:373)age o(cid:396) des(cid:272)(cid:396)i(cid:271)ed i(cid:374) te(cid:396)(cid:373)s of su(cid:272)h da(cid:373)age(cid:863) Some people have better emotional tolerance to pain, sometimes you cannot pinpoint source of pain; pain is what they say it is. Acute pain usually temporary related to injury resolves during normal healing period, whereas chronic pain last 3-6 months or outlasts usual healing process. Transduction, substances such as (sp, prostaglandin) released, creates action potential that travels to dorsal horn of spinal cord, where transmission occurs, substance p allows it to be transferred and travel up to the brain. Brian tries to modulate with endorphins, ne, opioids to relieve pain, however these chemicals are short-lived and broken down quickly. Use antidepressants specifically that act on ne pathways which are important in pain modulation: peripheral pain. Nociceptive pain-due to injury or inflammation to a body structure.