BISC 220Lg Lecture Notes - Lecture 6: Aldosterone, Thyroid-Stimulating Hormone, Somatostatin
11 Apr 2016
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Target cell because it has receptors for specific hormone. Cell that secretes signal can also have receptor for signal:; autocrine signaling. Most abundant: albumin absorb osmotic pressure nonspecific carrier for all lipophilic hormones. Secretion of carrier protein is regulation of hormone. Lipophilic in unbound state: can diffuse through plasma membrane. Progesterone: female sex hormone that has plasma membrane receptors. Pituitary underneath hypothalamus; above end of bony pallet hypothalamus neurons: Affects smooth muscle in memory glands and uterus. Oxytocin evidence in animals pretty strong; not very strong in humans. Downside to oxytocin: more narrowmindedness; reinforces perception of otherness; racism. Cells in pituitary release hormones into the blood; 8 different cell types in anterior pituitary; each one release one of the eight hormones. Each anterior pituitary hormone, there is releasing hormone; some have release inhibiting hormones. Neurons of hypothalamus are releasing releasing hormone gnrh (gonadotrophic releasing hormone) Only place where iodine is needed in body.
