BIO 365S Lecture Notes - Lecture 4: Tryptophan, Anterior Pituitary, Posterior Pituitary

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16 May 2018
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Three Major Classes of Hormones:
ØSteroidmade from cholesterol
ØPeptidesynthesized by linking amino acids
ØAminesynthesized from either tyrosine or tryptophan
Amines behave like peptide hormones. Thyroid hormones. Some can
behave like steroids.
Sources of Steroid Hormones:
Primary
¨ Adrenal Cortex
¨Gonads
also…
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¨Placenta: continually releases female sex hormone (progesterone) during child birth until
placenta comes out. This helps no ovulating.
Peptide = lipophobic
Steroid = lipophilic
Steroid hormones can have difficulty to be carried by blood, so need
carriers.
Hormone Interactions:
¨Synergism: effect of 2 or more hormones on same parameter is greater than additive.
¤ 1+1>2 e.g. testosterone and growth hormone
¨Permissiveness: one hormone is needed for another to exert its full effect (first hormone has
no direct effect on parameter)
¤1+1=1 e.g. Thyroid hormone and GH
¨_Anatognism: hormones have opposing effects
¤ 1+1=0 e.g. Insulin and Glucagon
Thyroid hormone: steroids, metabolism, nothing to do with cell growth.
Antagonism: may waste energy because gives no resulting effect.
Hormone interactions: different pathways for each hormone.
¨Epinephrine alone weakly stimulates lipolysis. Sall amount of thyroid hormones present, same
about epinephrine stimulates lipolysis much more powerfully. Thyroid hormone has no affect
o lipolysis. Iteractio of these horoes…
¤-Permissiveness
Hormones can be categorized by connection to the hypothalamus
Pituitary gland: has 2 different tissues. Anterior = endocrine cell,
whereas posterior = neural tissue.
Hypothalamus: controls autonomic nervous system and releases a lot of
hormones, which goes to anterior pituitary gland to release a second
hormone.
The posterior pituitary:
a neural connection
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Document Summary

Placenta: continually releases female sex hormone (progesterone) during child birth until placenta comes out. Steroid hormones can have difficulty to be carried by blood, so need carriers. Synergism: effect of 2 or more hormones on same parameter is greater than additive. Permissiveness: one hormone is needed for another to exert its full effect (first hormone has no direct effect on parameter) Thyroid hormone: steroids, metabolism, nothing to do with cell growth. Antagonism: may waste energy because gives no resulting effect. Sall amount of thyroid hormones present, same about epinephrine stimulates lipolysis much more powerfully. Hormones can be categorized by connection to the hypothalamus. Anterior = endocrine cell, whereas posterior = neural tissue. Hypothalamus: controls autonomic nervous system and releases a lot of hormones, which goes to anterior pituitary gland to release a second hormone. The posterior pituitary: a neural connection to the hypothalamus.

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