BIO 365S Lecture Notes - Lecture 16: Pulmonary Vein, Gap Junction, Pulmonary Artery

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16 May 2018
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At 3 weeks, when heart starts beating. Faster for small animals so faster
for fetus.
Right = deoxygenated, comes from vena cava (body), goes to right atria,
goes to AV valve in one direction because the valve can only move in
one direction in right ventricle (small, pump #1, sends blood to lungs to
get O2). Blood then goes through pulmonary artery (definition = bring
blood out) to lungs.
Journey is not long. Both heart and lungs are in thorai age, so that’s
why right ventricle is small.
Left: goes back through pulmonary veins (definition = bring blood back),
go through left atrium, goes through left AV/bicuspid/mitral valve, into
left ventricle (pump #2, big, squeeze blood farther throughout the
body, so muscle is much bigger, squeezes blood out to the aorta =
recoil back slowly in order to push blood out).
Atrium and ventricles work together. When atrium contract, ventricle
releases and vice versa.
Cardia muscles have well organized fibers, very similar to skeletal
muscle (used to create big force).
Intercalated disks = separation b/w one muscle fiber with another one.
Gap junctions like ion hannels, ut they’re not losed, stay open so if
one of the cell generate an action potential, those cations can quickly
go through gap junctions to other cells.
Heart geenrates electrical signals first, go towards atria, contract with
the help of desmosomes to squeeze them together. Then signal goes to
ventricles as I also contract and then depolarize together because of
the gap junction and contract together bc of desmosomes = mechanical
fore onduts to all the fiers. Don’t want all 4 hambers to contract
together.
Need to know which one contacts with which and how the blood flows.
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The pumps and pipes analogy of
the heart
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Document Summary

Faster for small animals so faster for fetus. Blood then goes through pulmonary artery (definition = bring blood out) to lungs. Both heart and lungs are in thora(cid:272)i(cid:272) (cid:272)age, so that"s why right ventricle is small. When atrium contract, ventricle releases and vice versa. Cardia muscles have well organized fibers, very similar to skeletal muscle (used to create big force). Intercalated disks = separation b/w one muscle fiber with another one. Gap junctions like ion (cid:272)hannels, (cid:271)ut they"re not (cid:272)losed, stay open so if one of the cell generate an action potential, those cations can quickly go through gap junctions to other cells. Heart geenrates electrical signals first, go towards atria, contract with the help of desmosomes to squeeze them together. Then signal goes to ventricles as i also contract and then depolarize together because of the gap junction and contract together bc of desmosomes = mechanical for(cid:272)e (cid:272)ondu(cid:272)ts to all the fi(cid:271)ers.

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