BCMB 230 Lecture Notes - Lecture 15: Basilar Membrane, Cochlear Duct, Oval Window
16 Dec 2016
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• Inner ear is fluid filled
• Middle ear
o Amplifies signal
• Oval window has a much smaller area in comparison to the tympatic membrane
focusing signal
• Three areas of fluid in the cochlea
o Cochlear duct
▪ Inside
• Organ of corti
• 2 membranes tectorial and basilar
▪ Different spots on the basilar membranes are stimulated depending on
the feuecy pitch of the soud.
▪ Loudess: feuecy Itesity of the soud ae ad ho ay actio
potentials
▪ Loss of elasticity in basilar membrane- Causes us to not be able to hear
high pitched frequency
▪ QUESTIONS FROM EXAM 1 AND THURSDAYS READING ARE ON THE EXAM
FOR BONUS
Muscle
• 3 types
o Cardiac
▪ Found in heart
o Smooth
▪ Throughout the and skin (erector pilli muscles in the sikn)
o “keletal EXAM 2
▪ Contractile Proteins
• Actin- thin filament- String of spheres, each molecule has a
myosin binding site
• Myosin-Thick filament- Looks like a sperm cell. Energized and non
energized conformation. Head conformation determines energy.
o 2 binding sites
o ATP and actin binding site
o Binding to the actin is required for contractions.
▪ Structural proteins
• Hold actin and myosin in their positions
• Z proteins
• Titin
▪ Control- Associated with the actin
• Troponin- Binds with calcium
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