ANPS 020 Lecture Notes - Lecture 26: Natriuretic Peptide, Extracellular Fluid, Hydrostatics
3 Apr 2019
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Electrolytes are unevenly distributed between plasma, interstitial fluid, and intracellular fluid. Nonelectrolytes usually formed by covalent bonds, so don"t dissociate. Hydrostatic pressure pressure of the fluid in a system. Osmotic pressure measure of the tendency of a solvent to move into a more concentrated solution. Anything that changes solute concentration in a compartment leads to water movement: water follows solutes. Healthy people maintain osmolality of body fluids within a narrow range (280-300 mosm). Water balance is maintained by: thirst mechanism, blood volume, antidiuretic hormone, electrolyte balance, atrial natriuretic peptide. Aldosterone reabsorbs na so increases blood volume and blood pressure. Anp decreases blood pressure and blood volume; suppress the release of adh, renin. Blood and tissue ph is maintained over a small range: normal arterial ph = 7. 35-7. 45. Only free h+ contribute to the acidity of a solution. Strong acid/bases can produce large changes in ph- because they dissociate completely.
