BSCI-2520 Lecture Notes - Lecture 18: Cerebroside, Phosphocholine, Liposome
26 Apr 2016
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Document Summary
Soluble in organic solvents and mostly amphipathic (both polar and nonpolar) Carboxylic acid followed by long hc chain, the chains have even number of carbons because they add in c2 units, c16 and c18 are most common. Increasing unsaturation increases fluidity because there are more kinks and it is harder to pack them together and form bonds, it is liquid form: saturated: all single bonds in the long chain. Increasing number of carbons increases melting point: solid at room temp bc of all of the bonds between the relatively straight chains. Glycerophospholipids: based on glycerol-3-phosphate with two ester linkages = also a propane chain with ester on c1 and c2 and po3. 2- + x (alcohol) on c3: amphipathic, long nonpolar tails with polar heads, changing x on phosphate changes the name. Plasmalogens: contain ether linkage and cis double bond on c1, found in plasma membranes of nerves and cardiac cells.
