GEV 1050 Lecture Notes - Lecture 13: Institutional Review Board, Bioaccumulation, Ecotoxicology

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Toxins in an organism (higher concentration than in the environment itself) Variety of ld50s: aspirin, ethanol, at a certain level, causes death (lethal) in 50% of the cases// Human subjects, ethics, different reactions in different people. Rats, autopsies to see point of od, go through institutional review board. People (cid:272)o(cid:374)(cid:272)erned with lower levels of exposure over time (routine drug users) Flint michigan: lead leeched out of pipes into water, children exposed. Exposure to pesticides in the foot hills above and below pesticide use (where agriculture happened/runoff) (cid:272)hildre(cid:374)"s development hampered by exposure to pesticides. Also called social hazards: activities undertaken during your lifestyle, location, socio-economic status, behavior, both voluntary and involuntary. Smoking and damaging lungs= behavior (increases exposure to nicotine and carcinogenic) Not always behavior: also socio-economic status and food availability (food deserts), genetic predisposition to obesity. Cardiovascular diseases (heart) cancer, pulmonary disease (lungs) some related to aging, lifestyle, obesity (increased life span?)

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