NURS 472 Lecture Notes - Lecture 12: Acute Respiratory Distress Syndrome, Alkalosis, Hypoventilation

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If you have metabolic alkalosis your respiratory system kicks in to help out. In order to keep acid you breath slower so metabolic alkalosis causes hypoventilation. Ards= refractory hypoxemia --- we are not getting results with the treatment. Risk factors for ards--- sepsis, pneumonia, age (65 and older), comorbidities. Ronchi indicate exudate in the lungs (sounds like gurgling) Phase 1: injury reduces normal blood flow to lungs. Platelets aggregate and release histamine, serotonin, & bradykinin. Phase 2: those substances, esp, histamine inflame & damage alveolar-capillary membrane, capill. Permeability proteins & fluids leak out, increasing interstitial osmotic pressure & causing pulmonary edema. Phase 4: blood flow & fluids is the alveoli damage surfactant & impair the cell"s ability to produce more. As a result, alveoli collapse, impeding gas exchange & lung compliance. Phase 5: sufficient oxygen cannot cross the alveolar-capillary membrane, but carbon dioxide (co2) can and is lost with every exhalation. O2 and co2 levels in the blood.

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