BIOL 1107 Lecture Notes - Pattern Recognition Receptor, Innate Immune System, White Blood Cell
Document Summary
Be able to describe how pathogens are identified by the immune system. Compare and contrast the functions of the innate and adaptive immune systems. In mammals, the 3 lines of defense are: physical barriers - mucus layers created by epithelium are important. Should you ever be exposed to the same kind of bacteria or virus again, for example, your adaptive immune system would be able to more efficiently fight it off through the mechanisms of immune memory. The pathogen may have pathogen-associated molecular patterns that will be recognized by pattern recognition receptors on immune cells. Mammals have several classes of pattern recognition receptors, one of which is the toll-like receptors. Toll-like receptors are found on the cell surface and within the cell on various membrane-bound compartments. Inflammation is the immune system"s way of activating and responding to a perceived threat. Recruit cells to the area using chemokines.
