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MEDICAL TECHNOLOGY Lecture 1: PLATELET STRUCTURE AND FUNCTION

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mariposa
28 Oct 2022
School
Lyceum of the Philippines University
Department
Health Sciences
Course
MEDICAL TECHNOLOGY
Professor

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Document Summary

Other name: thrombocytes or sequestered in the spleen thromboplastids. Nv: 150 - 400 x 10^9 / l. Platelet distribution width (pdw): classify particles between 2-25 fl particle size. Histogram: shows platelet size distribution as right skewed, single peak. Wright-stained smear circular to irregular and granular. In the blood vessel: platelet along with rbc is in the center, wbc roll up in the margin, wbc and platelet in and out of white pulp of spleen (not rbc) Parts of platelet: chromomere central portion, granular, hyalomere surround chromomere, non- granular, and light blue color when stained by wright-stain. Platelet count: normal: 150-400 x10^9/l, after 65 y. o. Platelets count only represent 2/3 of the platelet population and is found in (splenectomy/removal of spleen: increase platelet count) Prematurely release from megakaryocyte due to thrombocytopenia in peripheral circulation because of high demand. >6 um, mcv: 12-14 fl larger than normal platelet. Carry ribosomes and fragment of rough er identification: stained by thiazole orange (rna stain)

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