KINESIOL 2Y03 Lecture Notes - Lecture 14: Fibrocartilage, Proteoglycan, Blood Cell

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Cartilage cells matrix (cid:8869) 70-85% water, protein, proud substance - collagen + proteoglycans. Hyaline, elastic, fibrocartilage during development, repair (cid:8869). bone develops from cartilage most common. Crticu) dr joints, nose strongest support also in joints flexible. Extracellular bone matrix bone cells trapped in matrix-constantly break down. 65% inorganic - crystallized mineral salts (cid:8869))hydroxyapatite: calcium phosphate crystals. 35% organic - collagen/proteoglycans, water (cid:8869) flexible strength wso mineral. Form matrix vesicles of cat and pos hydroxyapatite. ~release vesicles + bone matrix formed responsible for ossification (bone formation) 4 stem cells: can become osteoblasts or chondroblasts. Located in cavity (lacunal inactive produce components necessary to maintain bone matrix. Acid + enzymes dissolve calcium, phosphorus, and collagen. Woven bone (cid:8869) randomly oriented collagen fibers (development + repair) (cid:8869)remodeled. Lamellar bone (cid:8869) mature bone organized in sheets or layers (lamellae) (cid:8869) spongey (cancellous trabecular) Inside of bone: 20% of skeleton. Outside of all bones + shafts of long bones.

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