1105 Lecture Notes - Lecture 1: Electronegativity, Glycolysis, Activation Energy

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11 Jan 2023
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Some atp is generated in glycolysis and krebs cycle by substrate-level phosphorylation. An organic molecule transfer to adp to form atp. Make only 10% atp (krebs cycle and glycolysis) 90% of atp is made by oxidative phosphorylation. Exergonic - release of energy (delta g is negative) Endergonic - absorbed of energy (delta g is positive) Exergonic and endergonic are not spontaneous because of the activation energy. Translocation/pyruvate oxidation step 2 (occur in glycolysis and kreb cycle) Pyruvate enter the mitochondria in the translocation rxn. Leaves acetate behind which bond to coenzyme a. 1 nadh released per pyruvate (produce nadh to transfer the electrons) Don"t need to draw adp, fad, nad but need to recognize. Adp has energy because it has phosphate bonds. If electronegativity moves orm low electronegativity to high directly, then it can bust therefore it needs to follow the steps by going slowly. Graph of flow of energy and energy given.

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