NURS 203 Lecture Notes - Focal Segmental Glomerulosclerosis, Membranous Glomerulonephritis, Maltese Cross
Document Summary
All the glomeruli are diffuse, too many nuclei. Example: scarlet fever 2 weeks ago, presents with hematuria, rbc casts, mild to moderate proteinuria, hp, periorbital puffiness. Em: lumen of capillary, bump on lumen is endothelial cell, underneath is bm (grayish), and epithelial cells under. Has boulders that are denser than the normal glomerular bm these are immune complexes. In this case, it the bacteria is the ag-ab immune complexes. Closer to epithelial side, therefore they are subepithelial deposits hence post strep gmn. Example: 35 y/o female with + serum ana with a rim pattern (meaning you have anti dna. There are 6 types, and the important one to know is type iv, which is a diffuse proliferative glomerulonephritis, which is the mc overall one seen in lupus. Has many nuclei, therefore proliferative; has wire loops. (orient to. Em) deposits in bm are anti dna deposits.
