HLSC 2460U Lecture Notes - Nephron, Cardiac Arrhythmia, Hypernatremia
Document Summary
An excessive accumulation of fluid within the interstitial spaces (too much water in that space) To understand this, we have to go back to anatomy Capillary w/ an arteriole and venule (capillary bed) A cell is supposed to receive water and nutrients from the capillary. Water that comes into the capillary from the arteriole) This pressure pushes the water as a filtrate into the interstation. The higher the bp the more filtration, lower and lower. Osmotic pressure induced by proteins in the plasma. In the venules, there are a lot of proteins in the plasma. These proteins exert some osmotic pressure to attract water back into the venule from the interstation. This induces reabsorption of the water that was filtered back into the venule. This is dependent on the concentration of proteins in the plasma, not bp! Low protein in plasma = low oncotic pressure therefore less water reabsorbed.
