MELS223 Lecture Notes - Lecture 4: Asymptomatic Carrier, Myalgia, Headache
6 Sep 2013
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Document Summary
Avian influenza: h5n1 low infectivity, high mortality. To study the natural history of four infectious diseases. To distinguish between different bacterial strategies which lead to evolutionary success. To discuss the importance of carriage of pathogens. The science of epidemiology p. 942 (12th ed. carriers p821-822; influenza p862 864; tuberculosis p854 856; epidemiology pp. Encountering a pathogenic microorganism: period of multiplication. End point = want to colonise and invade, replicate in our bodies. Host provides: nutrients, water, temperature, osmolarity, ph conditions. Remain in host long term, disease (chronic). Lots of opportunity to transmit to a new host. Remain in host short term, but high infectivity (acute) Remain in host, no symptoms of disease ( asymptomatic, latent) Symptoms: chills, headache, dry cough, high fever, myalgia. Virus is shed before the person is ill! Acute infection, large amount of virus is shed. Replicates, enters, into cyst and travels around. Wall off and lay down calcium around the lesion = healed lesion.
