MELS223 Lecture Notes - Lecture 9: Antimicrobial Resistance, Neisseria, Legionella
Document Summary
Transmission and prevention the chain of infection. With attention to transmission in a hospital setting. How transmission of microbes can be prevented in a hospital. How to break the chain of infection. Aim is to protect both the patient and healthcare provider. Viruses: hepatitis b, c, influenza, cold" viruses, norovirus, hiv. Virulence measure of an organism"s ability to cause disease. Immune evasion capsules, biofilms, antigenic variation, resistance to phagocytosis, Place in which an infectious agent may survive but not multiply: humans, animals (zoonoses, environment air, water, soil, fomites. Human reservoirs: people with acute or subclinical infection: pathogen infected but no signs of clinical disease= early infection / resolving infection / chronic carriers. Prevention : screening/ diagnosis treat carriers (mrsa) / infections. Respiratory tract (mucosal secretions: cold, influenza, respiratory bacteria, neisseria meningitides. Gastrointestinal tract: salmonella, shigella, campylobacter, giardia, Contact, droplet, airborne, common vehicle, vector-corne (uncommon in health care setting)