BCH2011 Chapter Notes -Hydrolysis, Beta Barrel, Intermolecular Force

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Proteins are polymers of amino acids, with each amino acid residue joined to its neighbor by a specific type of covalent bond. The term residue reflects the loss of the elements of water when one amino acid is joined to another. Proteins can be broken down (hydrolysed) to their constituent amino acids by a variety of methods. All 20 of the common amino acids are alpha-amino acids. They have a carboxyl group and an amino group bonded to the same carbon atom (the alpha carbon). They differ from each other in their side chains, or r groups, which vary in structure, size, and electric charge, and which influence the solubility of the amino acids in water. For all the common amino acids except glycine, the alpha-carbon is bonded to four different groups; a carboxyl group, an amino group, an r group, and a hydrogen atom. The alpha-carbon atom is thus a chiral center.

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