PSYC 001 Chapter Notes -Transcranial Magnetic Stimulation, Tricyclic Antidepressant, Psychodynamic Psychotherapy
Document Summary
Trephination(small hole cut in skull to relieve spirits. Suspected witches were either burned stake or drowned (float test) Impurities float, if she sank, she"s pure (but dead) ! Among first of pharmaceuticals to treat depression. Mao = enzyme converting serotonin > chemical form that lowers serotonin levels. Inhibits action of enzyme > allows more of neurotransmitters to stay active in synapse for longer time > improves mood. Interacts w/ many foods and common drugs to produce undesirable/dangerous side effects. Not presently prescribed for depression for this reason. New transdermal patch > allows administration of. Mao inhibitor w/o having to enter digestive tract > provide benefits w/o food interaction risks. Used in chronic pain management, adhd, bedwetting. Blocks serotonin & norepinephrine reuptake almost equally. Make more respective neurotransmitters available in brain. I. e. dry mouth, weight gain, irritability, confusion, constipation. Drugs targeting only serotonin offered hope for treatment w/ fewer side effects.
