BIOL 171 Lecture Notes - Respiratory Alkalosis, Sodium Bicarbonate, Respiratory Acidosis

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9 Mar 2014
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Acids and bases ph the measure of acidity physiologic ph: 7. 35-7. 45. Acid: dissociates to form h+ ion; a compound (electrolyte) that ionizes in water and releases hydrogen ions (h+); a proton donor. Base: a compound that binds h+ (usually forms in water); a proton acceptor. Strong acids: hcl---> h+ cl- stays in ionic form; lots of h+ ions. Weak acid: h2co3--->h+ hco3- stays associated; few h+ ions. Strong base: naoh--->na+ oh- fully ionic; completely dissociates in water. Weak base: nahco3--->na+ hco3- do not fully dissociate. Sources of h+ cellular metabolism of carbohydrates, proteins and fats. Regulation of acid-base balance homeostasis of h+ concentration is necessary for normal cellular function. 3 major buffer systems slight negative charge, so absorb h+ protein phosphate absorb some h+ carbonic acid-bicarbonate. Hcl + nahco3-->h2co3 + nacl strong acid buffer weak acid salt strong bases are neutralized by carbonic acid resulting in more bicarbonate being produced ex: sodium hydroxide.

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