BIOL 3300 Study Guide - Linkage Disequilibrium, Genetic Drift, Chromosome
Document Summary
Alleles from two different loci inherit as a package. The two loci are in linkage equilibrium (look at frequency calculations) The second example shows that the two loci are not in linkage equilibrium (b on a = Haplotypes or chromosome frequencies do change: haplotype: haploid genotype (ex: gametes, organelle genomes) Ab = 3/25 = 0. 12 ab = 8/25 = 0. 32 ab = 2/25 = 0. 08. Ab = 4/25 = 0. 16 ab = 9/25 = 0. 36 ab = 1/25 = 0. 04. Population admixture (2 genetically distinct populations accidentally put together) Because of selection these two loci are not in equilibrium. Not necessary to do all three of the criteria to determine whether in equilibrium or not. Finite population size, a really small population size. Mutation occurs on chromosome with ab: 4 possible haplotypes: ab, ab, ab, ab, ab not observed over time recombination will occur and result in crossing over.
