CHEM 1004 Lecture Notes - Paul Erlich, Alternative Medicine, Arsphenamine

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Prefixes and suffixes: hyper :more than normal vs. hypo :less, cardio:related to heart, gastro:related to gi system (often stomach, myo:muscle. Inter:between: poly:many, dys: painful,bad,difficult, osteo:pertaining to bone. Algia:pain in a part ie neuralgia (nerve pain) Pharmacokinetics: studies rates of change of drug concentrations in the body and includes rates of absorption, distribution, metabolism and excretion of a drug. Drug dependence and addiction: addiction can be viewed as the extreme on a continuum of involvement with drug use, occasional use -> frequent use -> physiological dependence -> compulsive use- > overwhelming involvement : addiction. Criteria for addiction: upon termination of the drug"s use, the addict suffers through a withdrawal syndrome (abstinance syndrome) Three types of drugs producing withdrawl syndrome: depressants : alcohol, benzodiazepines, barbiturates, opiates: heroin, morphine, methadone, stimulants: cocaine, amphetamines,caffeine. 50% receive real drug: neither group knows which, compare results. In some cases (particularly pain killers) placebo effect can be 30-40%