BIOSC 0150 Lecture Notes - Mucolipidosis Type Iv, Lysosomal Storage Disease, Mina Bissell
Document Summary
Ph 5, 100x more acidic than cytosol found in animal cells function in defense, maintaince, development. Need atp to cross into lysosome: need protein pump h+ into lysosome to keep lysosome acidic, mucolipidosis type iv. Just because of one mutating one lysosome/protein: have gfp (from jelly fish) show green light. Principle site of atp production in aerobic cell. Site of cellular respiration: glucose and fatty acids make atp. Have their own dna separate from the cell dna. Outer is 50:50 lipid:protein allows the passage of small particles. Membrane bound sacs- thylakoids which contains chlorophyll and enzymes that absorb light and generate atp during photosynthesis. Specialized compartment bound by a simple membrane. Transfer h ions to o creating hydrogen peroxide as a byproduct. Network of interconnected fibers that extend through cell. Functions/characteristics: provide support, maintain shape, dynamic, allow motility. 3 main components: microtubules-thickest, microfilaments-thinnest intermediate-filament. 2 polypeptides: alpha tubulin, beta tubulin. Elongate by adding tubulin on the end.
