PSYC 3403 Study Guide - Midterm Guide: Naltrexone, Cirrhosis, Alprazolam

• School: Carleton University
• Department: Psychology
• Course: PSYC 3403
• Professor: Tarry Ahuja

Document Summary

Enteral: oral (mouth, must be g. i. resistant, liquid vs. tablet, passive diffusion, lipid diffusion, lipid solubility, disadvantages. Drug distribution: only a small portion of the drug is actually interacting with target receptors (side effects, oral, through gi tract into portal system, drug enters central circulation to heart, drug may be metabolized by gi tract or liver, alcohol dehydrogenase found in gi tract and liver, liver contains drug metabolizing enzymes, grapefruit can decrease enzymes. Membranes, which affect drug distribution: cell membranes, lipid soluble (passable, water soluble (cannot pass, capillary vessels, tiny blood vessels with single cell walls, cell walls have small pores, pores allow for passive diffusion, entry into body tissue depends on. Lipid solubility of drug (smaller better/lipid soluble = better: placental barrier, drugs cross the placenta via passive diffusion, the placental barrier is not selective, similar concentration between mother and fetus, placental barrier is not blocking anything.