BC 351 Lecture Notes - Enzyme Kinetics, Reaction Rate Constant, Rate Equation
Document Summary
A x d [ x ] dt. A of a reaction to the concentration of reactants. The rate constant is a proportionality constant that relates the rate. It reflects the probability that a reaction will occur. High rate constant high probability fast rate. Hand grabs marble moves above the box moves to second box marble dropped. At low [s], takes more time for enzyme to find substrate. At low [s], increases in [s] make a large difference. Substrate concentrations that cause every enzyme to be in the bound form. A reflection of the enzyme"s to convert time at saturating conditions. The rate constant of the rate-limiting step of the reaction at saturating conditions. Can be thought of as measure of enzyme"s affinity for substrate; specificity. V0 = vmax = kcat [e]t kcat used to measure efficiency. At low [s] kcat/km used to measure efficiency. Symptoms: seizures, mental retardations, dislocation of the ocular lenses and often times will lead to death.
