NUTR 3210 Study Guide - Epithelium, Scurvy, Dental Caries
9 Oct 2012
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Vitamin d from diet & sun. Beta- carotene retinol if need vita: regulated by retinol- rbp. Retinol (made in liver) esterified to retinyl palmitate for transport in chylomicron or storage in liver: palmityl coa donates palmitate. Retinol must combine with rbp for transport in the blood. Retinyl esterase activity regulated by levels of retinol- rbp (in liver: retinyl palmitate retinol (via retinyl esterase) Retinoic acid is active form of vit. a: cells take up retinol and convert it into retinoic acid. Dbp transports: d3, 25- oh- vitd, 1,25- diohvitd. D3 in animals, fortified foods & supplements. 25- oh vit d aka calcidiol homeostatic set point. 1,25- di oh vit d aka calcitriol active vitd. D2 is less bioactive then d3. Vitd3 25- oh vit d (enzyme 25- hydroxylase) 25- oh vitd 1,25- dioh vit d (enzyme 1- hydroxylase) With viamin a, retinol made in liver and circulated bound to rbp.
