VETS3050 Study Guide - Final Guide: Dry Eye Syndrome, Sedative, Cefalexin
Document Summary
All things are poison, and nothing is without poison; only the dose permits something not to be poisonous . Drug action the initial consequences of drug-receptor combination (binding: eg adrenaline binds to adrenoreceptors in the heart to increase cyclic amp (camp) in cells. Drug effect biochemical and physiological changes that occur as a consequence of drug action: eg adrenaline causes increased heart rate and cardiac output. Pharmacodynamics effect of the drug on the organism or body, involving the binding of the drugs to cells. Receptors are regions on proteins associated with: Ion channels voltage-gated sodium channels: enzymes by targeting an enzyme catalyzing another reaction, that reaction can be controlled (nsaids target cox. 1 and cox2 to prevent conversion of arachidonic acid: carrier molecules glucose, other proteins ribosomes. Pharmacokinetics response of the organism or body to the drug, Receptor families involving distribution, metabolism and elimination of the drug: three families are associated with receptors on cell.
