PHSI2006 Study Guide - Final Guide: Ascending Limb Of Loop Of Henle, Renal Glucose Reabsorption, Descending Limb Of Loop Of Henle

• School: University of Sydney
• Department: Physiology
• Course: PHSI2006
• Professor: phsi2006

Document Summary

Descending limb of loop of henle: impermeable to solutes, permeable to water 10-15% water reabsorbed. So osmolality of the fluid decreases as you go along thick ascending limb. Early distal tubule: impermeable to water, permeable to solutes. 10% solutes= na and cl ions: in basolateral membrane there is the na pump. 83: in the apical membrane there is a na- cl cotransporter- both go in. Na goes in and goes out the baso side through the na pump. The cl goes in and goes out the baso side through cl channel: water stays. Water reabsorbed- this is variable and depends on amount of adh present in body: two different types of cells, principal cells, intercalated cells- type a, type b and non type a non type b. 84: both of the cells have the na pump in the basolateral membrane. Principal cells: apical sodium channel called enac (epithelial sodium channel).