IMED2004 Study Guide - Final Guide: Histone Deacetylase, Lysine, Acetyl Group

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22 Jan 2020
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Adds acetyl group onto lysine to remove charge to loosen dna packaging. Acetylate lysine residues on the amino terminal of histone proteins. Attach an acetyl group to selected lysine in the tail of histone proteins. Allowing greater accessibility to the underlying dna. The acetyl groups themselves are recognized by proteins that promote transcription. Compacted chromatin via hdac by de-acetylating it. An enzyme that removes acetyl groups from the tails of histone proteins. Its action often allows chromatin to pack more tightly. Stage of early development in mammals that consists of a hollow ball of cells. A fluid-filled sphere formed about 5 days after fertilization of an ovum that is made up of an outer ring of cells and inner cell mass. This is the structure that implants in the endometrium of the uterus. De novo methylation within somatic cells of developing embryo. A group of enzymes that add methyl groups to cytosine residues in.

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