BIOL10004 Study Guide - Final Guide: Autoradiograph, Missense Mutation, Restriction Enzyme

• School: University of Melbourne
• Department: Biology
• Course: BIOL10004
• Professor: Dawn Gleeson

Document Summary

Lecture 7 - gene interaction & lecture 8 - autosomal linkage (module 2) Unlike green/yellow and smooth/wrinkled in peas, sometimes genes can interact with each other to determine phenotype. Epistasis an allele at one gene locus masks the phenotypic expression of the alleles of another gene locus. Recessive epistasis - mice genotype aa or aa results in enzyme a present (black) genotype bb or bb results in enzyme b present (agouti) if bb or aa, no corresponding enzymes would be present therefore, B = no colour, b = colour expressed. A masks the e ect of the alleles at the i/i locus therefore a-b- and a-bb express the same phenotype ratio: 12a-; (9a-b- + 3a-bb) : 3 aab- : 1 aabb. Other interactions colourless colourless purple (needed a- or b- in the pathway) original ratio: 9 a-b- : 3 aab- : 3 a-bb : 1 aabb. Lecture 8 - two or more genes, autosomal linkage.