IMED1001 Study Guide - Final Guide: Basement Membrane, Basal Lamina, Salivary Gland
IMED1001'Tutorial'Summary'(Anatomy'lecture'CT1'and'Epithelial)'
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Basement!membrane!=!basal!lamina!!
- Non-cellular!
- Made!of!complex!macromolecules!
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Hollow!organs:!
1. Epithelium!
2. Basement!membrane!
3. Connective!tissue!
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Epithelial!function:!
1) Provides!covering/lining!
2) Allow!absorption/secretion!(gland!=!extension!of!epithelium)!
3) Barrier!(1st!line!of!defense)!
4) Diffusion!
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Cell!junctions:!!
1) Adhering!=!integrity,!prevent!disintegration!(eg.!Desmosomes)!
2) Occluding!=!prevent!passing!through!=!no!leakage!(in!gut)!
3) Gap!=!allow!small!substances!through,!mostly!for!communication!(found!in!heart)!
!
Endothelium!=!epithelial!of!BLOOD!VESSELS!
Epidermis!=!epithelial!of!SKIN!
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Simple!squamous!e.:!endothelium!=!allow!diffusion!of!nutrients!into!cells!from!blood!
Simple!cuboidal!e.:!secretory!=!salivary!gland!
Simple!columnar!e.:!absorption!=!gut!
Stratified!squamous!e.:!prevent!wear/tear!=!esophagus,!mouth,!anus!
Pseudostratified!columnar!e.:!respiratory!tract!(bronchus,!trachea)!
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Microvilli:!
- Cannot!be!seen!individually!
- Brush!border!
- ONLY!EM!
- Part!of!membrane!
- Increase!SA!hence!absorption!
- Folds!in!membrane,!specialized!cell!for!CSM!
!
Cilia:!
- Hair-like!!
- Projections!on!membrane!
- Not!part!of!membrane!
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Goblet!cells:!
- Stores!and!produces!mucus!
Document Summary
Imed1001 tutorial summary (anatomy lecture ct1 and epithelial) Hollow organs: epithelium, basement membrane, connective tissue. Epithelial function: provides covering/lining, allow absorption/secretion (gland = extension of epithelium, barrier (1st line of defense, diffusion. Cell junctions: adhering = integrity, prevent disintegration (eg. desmosomes, occluding = prevent passing through = no leakage (in gut, gap = allow small substances through, mostly for communication (found in heart) Simple squamous e. : endothelium = allow diffusion of nutrients into cells from blood. Stratified squamous e. : prevent wear/tear = esophagus, mouth, anus. Folds in membrane, specialized cell for csm. Membranous: nucleus, mitochondria, er, ga, vesicles, lysosomes, peroxisomes. Double membrane (nuclear envelope) w/ nuclear pores made of rings of protein: er. Ser: fats, steroid hormones, detoxify free radicals, neutralize toxins, calcium storage (usually for cell) Rer: phospholipids, proteins (usually for outside cell: ga. Glycosylation and sulfation of proteins: cytoskeleton. Microtubules: organelles position, support and cell division/shape (kinesin + intermediate filaments: mechanical strength. Enzyme that digests proteins/nucleic acids: peroxisomes.
