IMED2003 Study Guide - Midterm Guide: World Medical Association, Nuremberg Code, Organoarsenic Chemistry

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Declaration of helsinki (1964): addition to nuremburg code. Ethical principles for medical research involving human. The world medical association drew up the first version of the doh that broadened the concerns of the nuremberg code. Confidentiality of personal information of research subjects. Privacy regarding the use of identifiable human information. Seven revisions, with the last (64th wma general. Reported on the pathologic manifestations of untreated syphilis in several hundred white males. Designed as a prospective study to complement oslo. Initially not inherently unethical in 1932- no cure was available. Involved 6-8 months observation and then contemporary treatments such as salvarsan (organoarsenic), mercurial ointments, and bismuth (possibly mildly effective, but very toxic). Men were actively prevented from accessing treatment and exiting the study!! (unethical) The dependent variable in the tuskegee experiment (ie unknown), was whether persons with syphilis were better off without the treatment". The longest non-therapeutic experiment on human beings in medical history". Participants illiterate african americans from tuskegee,