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Midterm

IMED2003 Study Guide - Midterm Guide: World Medical Association, Nuremberg Code, Organoarsenic ChemistryPremium

2 pages66 viewsSpring 2018

Department
Integrated Medical Sciences
Course Code
IMED2003
Professor
Kellie Bennett
Study Guide
Midterm

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IMED2003: Revision 14 Notes
Declaration of Helsinki (1964): ADDITION TO NUREMBURG CODE
ETHICAL PRINCIPLES FOR MEDICAL RESEARCH INVOLVING HUMAN
SUBJECTS
The World Medical Association drew up the first version of the DoH that
broadened the concerns of the Nuremberg Code
Significant additions include:
‘Right to ‘privacy’
Confidentiality of personal information of research subjects
Privacy regarding the use of identifiable human information
Seven revisions, with the last (64th WMA General
Assembly) in 2013
Human Use of Human Beings:
1928:
Norwegian study
Retrospective
Reported on the pathologic manifestations of untreated syphilis in several
hundred white males.
Tuskegee Syphilis Experiment (1932-1972)
DESIGN:
Designed as a prospective study to complement Oslo
Initially not inherently unethical in 1932- no cure was available.
Involved 6-8 months observation and then contemporary treatments such
as Salvarsan (organoarsenic), mercurial ointments, and bismuth (possibly
mildly effective, but very toxic).
Men were actively prevented from accessing treatment and exiting the
study!! (UNETHICAL)
The dependent variable in the Tuskegee Experiment (ie unknown), was
whether persons with syphilis were better off without the treatment.
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