PODI4203 Final: General Medicine Rotation

Estimate the pKa values for the functional classes represented by the given molecules. CEC H NH OH 10 o 10 o 10 O O 10 15 O 15 O 15 O O 15 o 20 o 20 O 20 O 20 O 20 O 25 O 25 O 25 O 25 O 25 O 30 O 30 O 30 O 30 o 35 o 35 35 O 40 O 40 O 40 40 40 O 45 O 45 O 45 O 45 o 50 o 50 O 50 O 50 O 50 10 O 15 O 20 O 25 O 30 35 40 O 45 O 50

Indicate whether each structure is aromatic, nonaromatic, or antiaromatic. ENH O aromatic O aromatic O aromatic O aromatic aromatic O nonaromatic O nonaromatic nonaromatic O nonaromatic O nonaromatic O antiaromatic antiaromatic O antiaromatic O antiaromatic O antiaromatic

Indicate whether each structure is aromatic, nonaromatic, or antiaromatic. Treat all structures as planar aromatic O O aromatic O aromatic O aromatic O aromatic O nonaromatic O nonaromatic O nonaromatic O nonaromatic nonaromatic O antiaromatic O antiaromatic O antiaromatic antiaromatic antiaromatic