BIOL 200 Study Guide - Midterm Guide: Transcription Factor Ii F, U2Af2, Tata Box
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Lecture 2: chemical foundations ii: membranes cannot be traversed by charged or hydrophilic molecules, ex: calcium cannot cross (charged), sugars cannot cross (too large), but benzene can cross (hydrophobic, small) Lecture 3: chemical foundations iii: amino acids are compose of a central carbon, an amine (nh,+) an acid (coo-), and an r group. It is the r group which determines the aa"s properties. Lecture 5: overview of transcription and mrna formation: initiation begins when the rna polymerase ii binds to a promoter sequence in dna, creating a. When the first phosphodiester linkage between the rntp"s is catalyzed, the system enters elongation. Multiple poly ii molecules can transcribe the same template at the same time. The complex very stable and doesn"t disassociate until it recognizes a stop site. The speed is around 1000 nt/min: rna polymerase ii has a special domain called the carboxy terminal domain, which is long in conformation and has a heptapeptide repeat.