MBB 222 Study Guide - Midterm Guide: Membrane Transport Protein, Disulfide, Beta Turn
Document Summary
Porins are passive membrane transport proteins consisting of -barrel structures that provide a channel for ions and small molecules to pass through the outer membrane of gram- negative bacteria. Porin - a passive membrane transport protein that has a -barrel structural motif and is abundant in the outer membrane of bacteria, mitochondria, and chloroplasts. Alpha helix: backbone on inner portion of helix, side chains on outer portion // right vs left handed. Beta sheet: polypeptides are linear, stacked on top of one another // parallel vs antiparallel. Parallel: an amino acid on one strand interacts w/ 2 amino acids on opposite strand. Beta turn: c=o group of nth amino acid interacts with h-n group of n+3 amino acid (hydrogen bond). R groups on beta turns interact with polar solvent found outside proteins (hydrophilic). Understand the molecular interactions that stabilize a folded protein.