BIOC 2580- Final Exam Guide - Comprehensive Notes for the exam ( 84 pages long!)

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Lecture 1 - biological macromolecules & amino acids: 99% of the human body is made up of o, c, h, ca, n, ph mostly oxygen, small molecules: sugars, amino acids, nucleotides, fatty acids, simply carboxylic acid derivatives. Interconversions of these can store/release energy, which is the basis of metabolism: small molecules may be building blocks for macromolecules, macromolecules, proteins: chains of amino acids, nucleic acids: chains of nucleotides, polysaccharides: chains of simple sugars. 1. 2: protein molar mass is generally between 10 000 100 000 g/mol, kilodalton (kda): 1000 g/mol = 1 kda; 1 g/mol = 1 da, ex. Myoglobin, the protein that stores oxygen in the muscles, has a molar mass of 16 500 g/mol or 16. 5 kda: ex. 1. 3: 3 amino acids with a positively charged side chain (very polar, basic), 2 amino acids with a negatively charged side chain (very polar, acidic): Amino acids with negatively charged side chains: his, lys, arg.