BIOL 1090 Study Guide - Midterm Guide: Histone H3, Histone H1, Spindle Apparatus

• School: University of Guelph
• Department: Biology
• Course: BIOL 1090
• Professor: Jaideep Mathur

Document Summary

Genotypic ---> replication parental strand separates and synthesizes complementary strand makes 2 identical daughter strands. Evolutionary ---> mutation natural selection depends on population variation. Cyclic nitrogenous bases antiparallel strands double helix is right-handed hydrogen bonds between opposing bases hydrophobic interactions between adjacent stacked bases. B-dna is most common form composed of major and minor groove. 2 m of dna ts in 0. 002 mm cell. Connected by phosphodiester bonds base pairing is mediated by hydrogen bonds. Eukaryotic chromosomes are made of proteins, dna and rna. Pack dna (2 nm) as a negative supercoil into nucleosomes to produce an 11 nm bre. 146 nucleotide pairs wrapped 1. 75 turns around octamer of histones. Octamer of histones: 2(h2a, h2b, h3, h4) with a histone h1 backbone linker dna varies from 8-114 nucleotide pairs. 3) attach ber at many position to a non-histone protein scaffold create metaphase chromosome. Facilitate replication of the ends of linear dna.