[BIOL 1090] - Final Exam Guide - Everything you need to know! (56 pages long)

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Membrane proteins diffuse within the bilayer: movement of proteins is restricted, some do(cid:374)"t (cid:373)ove, rapid movement is limited by space, long range diffusion is slow, biochemical modification can greatly affect protein mobility in the membrane (signal transduction) Different membrane contain different types of lipids and proteins. Ions channels are selective, allowing only one types of ion to pass. Is introduced to living cell and tracked over time. Interconnected membrane cisternae, tubules and vesicles enclose a space (lumen) separate from the rest of the cell. 2 major sub-compartments: rough er: ribosomes bound to cytosolic surface; network of flattened sacs (cisternae) continuous with the outer membrane of nuclear envelope (peri-nulcear er, smooth er: no ribosomes; curved, higher tubule elements, smooth vesicles. In cytoplasm ribosomes synthesize polypeptides form mrna = translation. Cgn: (cid:862)sorting station(cid:863), sorts whether proteins should continue on to next golgi station or be shipped back to the er. Lysosomal membrane: glycosylated proteins: protected lining next to lumen.

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